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Scientific Program

  • 08:15-08:30 OPENING AND WELCOME
    S Antonarakis, A Kuliev
    8:30:-9:00 PLENARY LECTURE
    Whole Genome Sequencing: Application to PGT
    S. Antonarakis
     09:00-10:30 SESSION 1 - PROGRESS TOWARDS UNIVERSAL PGT
    Chairs:
    D Wells & S Rechitsky

    09:00-09:30 How close we are to Comprehensive PGT
    D Wells
    9:30-10:00 D Leigh
    10:00-10:30 PGT for De-Novo Mutations
    S Rechitsky
    10:30-11:00 COFFEE BREAK 
    11:00-11:30 PLENARY LECTURE
    Real-time imaging of preimplantation embryo development
    N Plachta
    11:30-13:00 SESSION 2 - ORIGIN AND MECHANISMS OF ANEUPLOIDY
    Chairs:
    A Handyside & J Vermeesch

    11:30-12:00 Mechanism of maternal age dependence
    M Herbert
    12:00-12:30 Origin of mosaicism and segmental variations
    Eva Hoffmann
    12:30-13:00 Meiomapping
    A Handyside
    13:00-14:00 LUNCH BREAK
    13:00-14:00 ACCEPTED POSTERS (pdf)
    14:00-15:30 SESSION 3 - FREE COMMUNICATIONS OC-01 to OC-06
    Chairs:
    K Xu & A Thornhill

    OC-01
    SUCCESSFUL HEMATOPOIETIC STEM CELL TRANSPLANTATION IN 62 CHILDREN FROM HEALTHY SIBLINGS CONCEIVED AFTER PREIMPLANTATION HLA MATCHING
    Umay Kara, B.; Gavaz, M.; Kumtepe Çolakoğlu, Y.; Yelke, H.; Pirkevi Çetinkaya, C.; Çetinkaya, M.; Kahraman, S..

    OC-02
    PATHOGENIC DNA VARIATION WITHIN ACMG SECONDARY FINDINGS GENES IN 18,000 HEALTHY INDIVIDUALS USING CLINICAL EXOME SEQUENCING FOR CARRIER SCREENING
    Mir Pardo, P.; Jiménez-Almazán, J.; Alonso, R.; Panadero, J.; Hernández-De-Diego, R.; Abellán, C.; Simón, C.; Martín, J..

    OC-03
    SELECTIVE TRANSFER OF EUPLOID NONCARRIER EMBRYOS WITH THE USE OF LONG-READ SEQUENCING IN PREIMPLANTATION GENETIC TESTING FOR RECIPROCAL TRANSLOCATION
    Chow, J.F.C.; Cheng, H.H.Y.; Lau, E.Y.L. Yeung, W.S.B.; Ng, E.H.Y.

    OC-04
    PGT-M FOR DE NOVO MUTATIONS – HAPLOTYPE DETERMINATION USING MORPHOLOGICALLY POOR EMBRYOS
    Stock-Myer, S.; Tang, P.; Twomey, A.; Kohfahl, A.; Shi, E..

    OC-05
    NOVEL APPROACH ENABLING THE SIMULTANEOUS DETECTION OF SNV AND CNV FOR PGT-M AND PGT-A USING A SINGLE-TUBE ASSA
    Y.Kimura, Y.; Laliberte, J. Kamberov, E.; Viotti, M.; Victor, A3; Brake, A.; Zouves, C.; Barnes, F.; Farmer, A.

    OC-06
    PGT-A METHOD ALLOWING COMBINED PGT-M FOR DETECTION OF HETEROPLASMY AND ESTIMATION OF MTDNA MUTATION LOAD IN EMBRYO BIOPSIES.
    Myers, S.; Jasper, M.

    15:30-16:00 COFFEE BREAK 
    16:00-16:30 PLENARY LECTURE
    Status and Impact of Prospective Carrier screening on PGT application
    J.L. Simpson
    16:30-17:30 SESSION 4 - PGT IN DIFFERENT SOCIAL SETTINGS
    Chairs:
    S Kahraman & S Hamamah

    16:30-17:00 Experience of Nationally-based PGT–
    S Hamamah
    17:00-17:30 PGT in Switzerland after Popular vote and Change of Legislation
    F Murisier
  • 09:00-09:30 SUMMARY OF HIGHLIGHTS PREVIOUS DAY AND INTRODUCTION TO SECOND DAY
    A Handyside
    09:30-10:00 PLENARY LECTURE
    Gene regulatory network in the context of genome instability in human embryo development
    T Voet
    10:00-10:30 SESSION 5 - DEVELOPMENTS IN PGD-A (PART I)
    Chairs: R Scott & D Cram

    Update of Randomized Controlled Studies on PGT-A Impact on Reproductive Outcome
    R Scott
    10:30-11:00 COFFEE BREAK
    11:00-13:00 SESSION 5 - DEVELOPMENTS IN PGD-A (PART II)

    11:00-11:30 Pregnancy outcome of transferred embryos with mosaicism and segmental variations
    F Fiorentino
    11:30-12:00 Impact of severe male infertility on chtomosome status of embryos and pregnancy outcome in younger women
    S Kahraman
    12:00-12:30 NIPT for PGT follow-up
    J Vermeesch
    12:30-13:00 Updated PGDIS recommendations for replacement of mosaic embryos
    D Cram
    13:00-14:00 LUNCH BREAK
    13:00-14:00 ACCEPTED POSTERS (pdf)
    14:00-15:30 SESSION 6- FREE COMMUNICATIONS OC07 to OC 12
    Chairs:
    G Harton & C Strom

    OC-07
    IMPACT OF CHROMOSOMAL MOSAICISM IN IVF OUTCOMES: EXPERIENCE FROM TWO HUNDRED MOSAIC EMBRYOS TRANSFERRED PROSPECTIVELY
    Spinella, F.; Biricik, A.; Minasi, M.G.; Varrichhio, M.T.; Corti, L.; Viganò, P.; Baldi, M.; Surdo, M.; Cotroneo, E.; Fiorentino, F.; Greco, E.

    OC-08
    SEGMENTAL ANEUPLOIDIES SHOW MOSAIC PATTERN REDUCING PREDICTIVE VALUE COMPARED TO HIGH WHOLE CHROMOSOME ANEUPLOIDIES REPRESENTATIVENESS
    Girardi, L.; Romanelli, V.; Fabiani, M.; Cimadomo, D.; Rienzi, L.; Ubaldi, F.M.; Serdarogulları, M.; Coban, O.; Findikli, N.; Boynukalin, K.; Bahceci, M.; Patassini, C.; Poli, M.; Rubio Lluesa, C.; Simón, C.; Capalbo, A..

    OC-09
    ASSESSMENT OF ANEUPLOIDY AND MOSAICISM CONCORDANCE BETWEEN DIFFERENT TROPHECTODERM BIOPSY SITES AND THE INNER CELL MASS EVALUATED WITH NEXT GENERATION SEQUENCING
    Tufekci, M.A.; Cetinkaya, M.; Cinar Yapan, C.; Kumtepe Colakoglu, Y.; Yelke, H.; Pirkevi Cetinkaya, C.; Kahraman, S..

    OC-10
    COMPARISON OF VARIOUS ANEUPLOIDY TYPES AMONG TWO TROPHECTODERM BIOPSIES AND A REST OF THE EMBRYO
    Navrátil, R.; Horák, J.; Horňák, M.; Kubíček, D.; Oráčová, E.; Janíčková, N.; Veselý, J.; Veselá, K..

    OC-11
    HIGH CONSISTENCY IN EMBRYO ANEUPLOIDY TESTING OF UNIFORM, MOSAIC AND SEGMENTAL ANEUPLOIDIES WITH THE APPLICATION OF A VALIDATED ALGORITHM
    Garcia Pascual, C.; Navarro Sánchez, L.; Navarro Gayá, R.; Rodrigo Vivó, L.; Garcia Herrero, S.; Campos Galindo, I.; Peinado Cervera, V.; Jiménez Almazán, J.; Simón Vallés, C.; Rubio Lluesa, C..

    OC-12
    WHAT TO DO WHEN THERE IS NO EUPLOID EMBRYOS? TRANSFER MOSAIC EMBRYOS OR PROPOSE ANOTHER PGT-A CYCLE?
    Cetinkaya, M.; Pirkevi Cetinkaya, C.; Tufekci, M.A.; Cinar Yapan, C.; Kumtepe Colakoglu, Y.; Yelke, H.; Kahraman, S..

    15:30-16:00 COFFEE BREAK
    16:00-17:30

    SESSION 7: EMERGING TECHNOLOGIES 
    Towards Embryo Therapy
    Chairs: S Antonarakis & C Simon

    CRISPR-Based Editing– Any prospect for PGT?
    H O’Neill

    Panel Discussion

  • 08:30-09:00 SUMMARY OF HIGHLIGHTS PREVIOUS DAY AND INTRODUCTION TO THIRD DAY
    JL Simpson
    09:00-09:30 PLENARY SESSION
    Clinical Impact of Maternal-Embryonic Communication at Implantation
    C Simon
    09:30-11:00 SESSION 8 - FREE COMMUNICATIONS OC13 to OC18
    Chairs: 
    C. Rubio & T Gordon

    OC-13
    CORRELATION BETWEEN ANEUPLOIDY, MOSAICISM AND MORPHOKINETIC DEVELOPMENT IN 1550 BIOPSIED BLASTOCYSTS
    Kumtepe Çolakoğlu, Y.; Tüfekçi, M.; Çınar Yapan, Ç.; Umay Kara, B.; Gavaz, M.; Yelke, H.; Pirkevi Cetinkaya, C.; Cetinkaya, M.; Kahraman, S..

    OC-14
    MOSAIC EMBRYO TRANSFERS – A COMPILED ANALYSIS OF PUBLISHED DATAViotti, M.OC-15 THE INCIDENCE AND ORIGIN OF CHROMOSOME ANEUPLOIDIES IN HIGH QUALITY KARYOMAPPING SNP PROFILES
    Hornak, M.; Horak, J.; Kubicek, D.; Navratil, R.; Zwinsova, B.; Tauwinklova, G.; Oracova, E.; Vesela, K..

    OC-16
    INTRACYTOPLASMIC SPERM INJECTION IS NOT NECESSARY AS A PREVENTIVE MEASURE AGAINST PATERNAL CELL CONTAMINATION IN PREIMPLANTATION GENETIC TESTING
    Lynch, C.; Cater, E.; Charitou, M.; Forbes, H.; Griffin, D.; Gordon, T.

    OC-17
    RECOMBINANT VERSUS URINARY GONADOTROPHINS: A PILOT STUDY TO EVALUATE PLOIDY STATUS OF EMBRYOS DERIVED FROM IVF.
    Leong, D.L.; Chen, J.J.; Wong, P.S..OC-18THE INSIGHTS OF EMBRYO MOSAICISM IN IVF CYCLESColl, L.; Parriego, M.; Garcia-Monclús, S.; Rodríguez, I.; Boada, M.; Coroleu, B.; Vidal, F.2; Veiga, A.
    11:00-11:30 COFFEE BREAK
    11:30-12:00 PLENARY LECTURE: Prospect of PGT for Epigenetic disorders-whole methylome and epigenetic analysis
    G  Kelsey
    12:00-13:30 SESSION 9 - ALTERNATIVE APPROACHES TO PGT 
    Chairs:  S Munne & L Gianaroli

    12:00-13:30 NIPGT multicenter concordance study
    C Rubio
    12:30-13:00 Blastocellic Fluid–based NIPGT
    L Gianaroli
    13:00-13:30 Further Data on Feasibility of PGT without IVF
    S Munne
    13:30-13:45 CLOSING REMARKS AND PRESENTATION OF NEXT PGDIS CONFERENCE
    A Handyside, A Kuliev
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